Alzheimer’s Therapy: Where Is The Cure Coming From

Alzheimer’s Therapy and the search for a cure has been going on for years. But, to date, no cure has been found and essentially Alzheimer’s is still a death sentence.
The World Health Organization (WHO), estimates that approximately 50 million people world-wide live with dementia, and approximately 60–70 percent have Alzheimer’s disease. Senior citizens, aged 65 and older, are the most vulnerable population for this incurable disease.Current treatments target the symptoms, such as memory loss and behavioral changes. However, in the last several years, the focus for the cure has shifted to finding a treatment against the the biological changes of this disease.

But the question is: should the cure just focus on one aspect of the disease or should researchers work on finding a combination therapy?

new comprehensive review published in the journal Neurology, asked this very question.

 

 

Alzheimer's Therapy

 

Alzheimer’s Therapy: Where Is The Cure?

A quick tabulation finds the following individual cures being used to treat Alzheimer’s:
  • Music therapy
  • Art Therapy
  • Psychological counseling
  • Physical Therapy
  • Drugs that attack beta-amyloid proteins and tau proteins in the brain
  • Chronic inflammation
  • Vascular dysfunction
  • Metabolic irregularities
  • Changes in gene regulation that may activate Alzheimer’s disease
  • A loss of connecting points between neurons, which then prevents information to flow between brain cells

 

Obviously, Alzheimer’s is a very complex disease, and none of the singular approaches have been successful. Therefore, according to this recent reviews conclusion, scientists should be focusing on a combination therapy approach.

 

The combination therapy approach should find drugs that each targets one of these key processes. In fact, note the authors, combination therapies are the standard of care for other major diseases of aging. These include heart disease, cancer, and hypertension.

 

No doubt, in their opinion, this same approach, will be necessary in treating Alzheimer’s. And, they may even find the cure for this intractable disease.

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